Magnetite-Containing Spherical Silica Nanoparticles for Biocatalysis and Bioseparations

Enhanced targeted MRI contrast using silica coated magnetite nanoparticles

Introduction MRI is a high spatial resolution non-invasive technique but it has low specificity for targeting explicit pathologies. In an effort to improve specificity, MRI contrast agents with strong paramagnetic properties such as Gadolinium have been developed. However recent reports of suspected deaths associated with gadolinium administration have severely limited their use [1-2]. Iron oxi...

Core-shell nanoparticles for medical applications: effects of surfactant concentration on the characteristics and magnetic properties of magnetite-silica nanoparticles

Objective(s): The use of cationic surface-active agents (surfactant) in the synthesis of nanoparticles, with formation of micelle, can act as a template for the formation of meso-porous silica. Changes in the concentration of surfactants can affect the structures and properties of the resulting nanoparticles.Materials and Methods: Magnetite nanoparticles were prepared as cores using the c...

Entanglements in polymer nanocomposites containing spherical nanoparticles.

We investigate the polymer packing around nanoparticles and polymer/nanoparticle topological constraints (entanglements) in nanocomposites containing spherical nanoparticles in comparison to pure polymer melts using molecular dynamics (MD) simulations. The polymer-nanoparticle attraction leads to good dispersion of nanoparticles. We observe an increase in the number of topological constraints (...

Magnetite nanoparticles for nonradionuclide brachytherapy1

Magnetite nanoparticles possess several properties that can make them useful for targeted delivery of radiation to tumors for the purpose of brachytherapy. Such particles are biodegradable and magnetic and can emit secondary radiation when irradiated by an external source. In this work, the dose distribution around a magnetite particle of 10 nm diameter being irradiated by monochromatic X-rays ...

Structure, entanglements and dynamics of polymer nanocomposites containing spherical nanoparticles